Abstract
A study was designed to investigate whether purple urine bag syndrome occurs in the presence of indican (3-indoxyl sulfate) and various kinds of bacteria. Eleven kinds of bacteria were used. and the following treatments were conducted.
1) Urine from a healthy man in eleven test tubes was supplemented with 3-indoxyl sulfate and each kind bacterium, respectively.
2) Physiological saline in the tubes with 3-indoxyl sulfate and each kind of bacterium, respectively.
3) Urine in the tubes without 3-indoxyl sulfate, but with each kind of bacterium, respectively.
4) Physiological saline in the tubes without 3-indoxyl sulfate, but with each bacterium, respectively.
The purple color characteristic of occured only in the test tubes containing 3-indoxyl sulfate and two kinds of bacteria (E. coli and Klebsiella pneumoniae). Thus occurrence of this syndrome seems to be influenced by not only bacteria and indican, but also urine pH and unknown substances in the urine.