Abstract
By the mutated strains of human type tubercle bacilli, reported previously by us, the aggultination for the tuberculous sera has been tested.
Among a total of 123 sera were 62 of pulmonary tuberculosis, 7 of extrapulmonary tuberculosis, 27 of non tuberculous diseases i. e, rheumatoid, syphilis, pregnancy, 27 of controls with tuberculin positive 15 cases and tuberculin negative 12 cases
The agglutinationtiters were ranging from 0 to 1: 2560. Sera of pulmonary tuberculosis showed on the average titers of 1: 320, of extrapulmonary tuberculosis 1: 80, of non tuberculous diseases 1: 40, and of controls 1: 10.
Titers above 1: 160 were acounted for 88.4% of pulmonary tuberculosis, except severe pulmonary tuberculosis, 14.8% of pregnancy, 28.6% of rheumatoid, 30.8% of syphilis and 15.4% of controls.
An attention should be paid to the fact that sera of severe pulmonary tuberculosis scarcely showed aggultination.
According to our experiments, there is a close correlation between the results of the aggultinationn by the mutated strains of tubercle bacilli and tuberculosis clinically.
This fact is also of significance in the evaluation of the aggultination test as a useful diagnostic procedure in suspected cases and also in prognostication
