Abstract
To get some aspect of the reserve storage of protein, especially of the mechanism of its mobilization, the extracellular fluid and plasma volume by NaSCN & T1824 were measured in 9 cases of unselected serositis with effusion (Tab. 1), in which the distribution of body water and plasma protein are supposed to change remarkably; simultaneously the electrophoretic protein analysis of plasma and effusion was done and serum potassium & chlor were measured by Kramer-Tisdall and SchaIes & Schales method.
Consecuently, at the begining of the convalescent stage, which is indicated clinically by diuresis and fever-drop, the increase of albumin was noticed with the decrease of extracellular fluid and increase of circulating plasma volume (Tab. 2 & Fig. 1), while, serum potassium increased remarkably at the bigining and decreased later (Tab. 4), And albumin % of effusion is larger than the other fractions and the albumin % of plasma protein in the acme and rather late stadium of the convalescence (Tab. 3).
So in these cases I believe that the source of water and protein in plasma is partly in the intracellular phase, and the change of the distribution of body water is significant for the protein metabolism or protein mobilization. And at that time albumin is supposed to be the most mobilized and utilized figure in the protein fractions