Abstract
Normal white male rabbits were injected with 5 cc of Ag-elecroid pull icc of physiological saline solution, two times at the interval of 24 hours, and the rate of pseudo-eosinophile cells, nuclear shift, pliagocytosis (indian ink particles), amounts of serum albumin and globulin, concentration of acid-fuccin in the aqua anterior, dead coli bacilli agglutinin value of serum and the aqua anterior were investigated. The results were as follows:
1) The phagocytosis of pseudo-eosinophile cells were accelerated by the injection of the said fluid and showed the maximum level on the lst-2nd day subsequent to the initial injection. It fell off to the original level by 7-16 days after the 2nd injection.
2) The amount of serum globulin increased by each injection and reached to the largest on the 1st-7th day subsequent to the 2nd injection. It returned to the original amount by 10 th day after the 2nd injection.
3) The counts of pseudo-ecsirophile cells increased gradually through the injections. They were highest figures on the 1st-3rd day subsequent to the 2nd injection and recovered their original figures by 6-9 days.
4) As for the nuclear shifts of pseudo-easinophile cells, left-shift was seen subsequent to the 1st injection; number of nuclei became minimum on the 1st-2nd day of 2rd injection; normal conditions were regained by 10 days after the 2nd injection.
5) The concentration of acid-fuccin in the aqua anterior decreased for 1-3 weeks subsequent to the injections.
6) Seven weeks after the preliminary immunization through dead coli bacilli, a group of rabbits were injected with the said fluid (Ag-elecroid). Their serum agglutinin increased by the 2nd week. No changes were seen in the aqua anterior.
7) Body weights and body temperature were not affected, practically.