抄録
The present paper is a intermediate report of autopsy of the late Mr. Kuboyama who was on the boat which was exposed to ash-fall near Bikini on March 1st, 1954. He was on the boat as chief radio operator for 2 weeks after the exposure.
The case developed acute radiation sickness in which radiation dermatitis and general myelopathia were the chief symptoms. For these symptoms, blood infusion, blood-plasma infusion, administration of antibiotics and other treatments were tried. In June the case developed liver disturbances with icterus and in spite of the findings of recovery in the blood picture, the case developed cholemia and ascites, and finally into leukemic blood reactions and the patient died on the 207th day of exposure. The result of autopsy is as follows:
1. Partial recovery picture in bone-marrows from general myelopathia. (Fig. 1)
2. Atrophic degenerations of lymphatic nodules. (Fig. 9)
3. Atrophy and function disturbance of testis. Swelling of the basal membrane of seminal tubules. (Fig. 10)
4. Atrophy of liver (860g) with inflammatory cell infiltration and slight cirrhosis. (Fig. 2, 4, 5)
5. Atrophic spleen (90g) with congestion. (Fig. 6)
6. Turbidity and swelling of pancreas (120g) with several small fat necrosis.
7. Serious cholernic nephrosis of kidneys (220g-left; 190 g-right). (Fig. 8)
8. Atrophic degeneration of myocardium Exudation in the interstice. Hemorrhage in the endocardium of left ventricle. Heart (320g). (Fig. 7)
9. Pneumonia with mixed infection of Aspergillus Fumigatus at the upper and lower lobes of left lung and the upper lobe of right lung. (Fig. 3)
10. Degenerative atrophy and partial acute inflammation of gastroenteric membrane and lymp hatic system.
11. Exudation at thoratic cavity (14cc-left; 17cc-right). Ascites (2, 600cc).
12. Remarkable yellow turbidity and partial hemorrhage at skin and mucosa.
13. Medium edema at bilateral insteps.
The most important findings were the fatal liver disturbances of the endodermal system. Generally, it is said that the liver is radiation-resistant. However, in the case of Mr. Kuboyama, not only was he externally exposured but also internally exposured and radiation hepatopathia shall be considered. Incidentally, Dr. Kimura's laboratory of Tokyo University Chemical Science Department found positive fission products in the liver tissues of Mr. Kuboyama. These data are under carefull consideration. Of course we cannot deny the secondary virus hepatitis, subsquent to the blood or blood-plasma infusion which was a thoroughly necessary measure in the treatment of the case. However, it may be considered that the said radiation hepatopathia induced the infection of virus hepatitis or in the least accelerated the development of virus hepatitis. The problem is, together with the infection of aspergillus fumigates pneumonia, one of the important questions in our studies.
