2013 Volume 52 Issue 3 Pages 212-218
The recent advancement of medical imaging technology enables us to obtain detailed and accurate information on morphology and functions in vivo. It is considered to be possible to predict the progress of a disease or the post-operative conditions prior to the surgery by combining the medical images and simulation techniques in the future. The paper presents an emerging method, patient-specific modeling and simulation, and its applications for cardiovascular diseases such as atherosclerosis and cerebral aneurysm. The vascular geometry is constructed from the medical images such as CT and MRI images of particular patients and the simulations are conducted to investigate the hemodynamics in the cerebral circulation and the cerebral aneurysm. The paper also provides the current research situation on the patient-specific modeling and simulation as well as its perspectives.