2025 Volume 64 Issue 4 Pages 348-356
Regenerative medicine is a research field aimed at restoring or replacing the function of tissues and organs damaged by accidents or diseases, and its social and medical significance is increasing globally. In recent years, the fabrication of three-dimensional structures using bio-3D printing technology has rapidly advanced. While 3D printers used in engineering and bio-3D printers share many technical elements, a clear distinction lies in the latter's use of cells and biomaterials combined as bioinks. This article provides an overview of regenerative medicine and bio-3D printing technology for creating tissues using cells. Furthermore, the text highlights the bio-3D printer using Kenzan method, which was developed in our laboratory. It briefly outlines the background of its development and its applications, which encompass image processing technology for system automation, and introduces animal experiments and studies involving human subjects.
