2012 Volume 88 Issue 4 Pages 130-142
An idiopathic disease with meningitis-like symptoms in infants, so-called meningitis named tentatively in infancy (SCMI), was endemic in Japan during the period of 30 years from the mid Meiji era to the late Taisho era (early 20th century). In 1923, Professor Ikutaro Hirai at the Kyoto University reported that SCMI was a chronic lead-poisoning diseases caused by white lead in the mothers’ cosmetic powder. In 1930, regulation of cosmetics including lead was stipulated in the Ordinance of the Ministry of Home Affairs. We previously reported the analysis of the articles published in a pediatric Journal, Acta Paediatrica Japonica, from 1923 to 1926. In this study, we reviewed 83 SCMI articles published in the journal from 1927 to 1930. This paper deals with review articles, case reports and articles on clinical findings, medical care and pathology/autopsy, which were all published during the period of 1927–1930. The next paper will deal with articles on laboratory examinations and experimental findings published in the same period.