During the last decade, it was discovered that low-power laser irradiation has stimulatory effects on bone cell proliferation and gene expression. The purposes of this review are to analyze the effects of low- power laser irradiation on bone cells and bone fracture repair, to examine what has been done so far, and to explore the additional works needed in this area. The studies reviewed show how laser therapy can be used to enhance bone repair at cell and tissue levels. As noted by researchers, laser properties, the combinations of wavelength and energy dose need to be carefully chosen so as to yield bone stimulation. With better study designs, the results will be more credible, allowing for greater recognition of advances in bone repair using laser therapy. Many studies on the effects of laser therapy on bone healing and fracture repair have used biochemical and histological methods. However, in order to establish the effects of laser treatment on bone, additional studies need to be performed using biomechanical tests, the ultimate evidence of bone repair. Finally, future studies are needed to demonstrate that the same bone stimulation effects occurring in animals may also be seen in humans.