1990 年 2 巻 2 号 p. 79-82
A nitrogen laser operating at 337 nm, with an energy density of 2.9 mJ/cm2/pulse, and pulse rate of 2-3 pulses/s, was used to irradiate the fungal suspensions. Irradiation for 2, 5 and 10 min produced moderate inhibition of the growth of Candida albicans(C albicans), and the number of colonies formed decreased with increasing exposure time. Such irradiation in the presence of methoxsalen caused a lethal effect on the fungus, but methoxsalen application alone did no harm to it, Exposure of the fungal suspensions for 20 min resulted in a lethal effect even in the absence of methoxsalen. The findings suggest possible application of the ultraviolet (uv) laser in photochemotherapy.
