LASER THERAPY
Online ISSN : 1884-7269
Print ISSN : 0898-5901
ISSN-L : 0898-5901
Original Articles
MEASUREMENT OF GaAlAs DIODE LASER ACTION ON PHAGOCYTIC ACTIVTY OF HUMAN NEUTROPHILS AS A POSSIBLE THERAPEUTIC DOSIMETRY DETERMINANT
Tsuyoshi OsanaiChiyuko ShirotoYasutaka MikamiEmiko KudouTakashi KomatsuKoujyun SuzukiShigeyuki NakajiTakashi KumaeKazuo SugawaraMutsuo Sasaki
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JOURNAL FREE ACCESS

1990 Volume 2 Issue 3 Pages 123-133

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Abstract

Recently, there has been an increasing amount of interest in the application of low reactive level laser therapy (LLLT) for pain attenuation or pain removal. However, the mechanisms by which LLLI- works are not yet full understood.
We measured the phagocytic rate using the luminol-dependent chemiluminescence method and a Neuroprobe 48-cell chemotaxis chamber to examine the chemical dependent motion of neutrophils with and without LLLT irradiation.
This study showed that at a 15-s exposure, 15, 30, 45, and 60mW output pewers (0.225, 0.45, 0.678 and 0.9 J) shortened the peak time compared with control; peak height increased at all four output powers; and neutrophil random motion count also increased across the board. At a 30-s exposure, doses of 0.45, 0.9, 1.356 and 1.8 J caused no significant shortening of peak time compared with control, but the peak height increased significantly for output powers of 15, 30 and 45 mW. Neutrphil random motion increased for the dose of 0.45 J (15 mW). For a 60-s exposure at the same output powers as above. doses of 0.9, 1.8, 2.7 and 3.6 J respectively, neither peak time nor peak height nor neutrophil random motion count showcd any significant difference compared with the controls.

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© 1990 Japan Medical Laser Laboratory
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