抄録
The progress achieved in biology during the last century has led to
development of mathematical and computer modelling of functioning regulatory
mechanisms (regulatorika) in molecular-genetic processes in living systems. In this
work we consider one of the possible methods for mathematical and computer mod-
elling of molecular-genetic systems regulatorika. The corresponding equations (in the
class of delay functional-differential equations) are developed, using the approaches by
B.Goodwin, Bl. Sendov, M. Eigen, B.A. Ratner, and taking into account of tempo-
rary relations, presence of multifunctional feedback and cooperative nature of processes
in cell’s regulatory loops. Results on the regulatorika for uniform molecular-genetic
systems, as well as the problem of the origin and development of hierarchical molecular-
genetic systems are considered. Results of using the considered method for analyzing
cell’s molecular-genetic systems in the presence of the alien genes (on the example of
hepatic cell infections by hepatitis B virus) are given.
