12-7 Small Animal Imaging for Drug Evaluation Using Synchrotron Radiation

Abstract

Microangiography with spatial resolution in the micrometer range was carried out to depict vascular responses of the pulmonary, coronary, cerebral, and renal arteries in rats using a real-time imaging system and a synchrotron radiation source at SPring-8. In imaging experiments, constriction and dilatation of small arteries were visualized in response to drugs.