Abstract
New high-density and low-power CMOS analog integrated circuits, CMOS source-drain follower and CMOS source-measure unit, have been developed for monolithically integrated biosensor array. These circuits do not disturb measured environment, can be fabricated by standard CMOS fabrication process, can be operated in subthreshold region, consist of 10 transistors for each basic circuit, and have good accuracy and weak dependence of temperature and device parameters. Several applications of integrated biosensor array have been investigated; pH detection, DNA detection, and bio-imagesensor utilizing photosynthesis protein complex, photosystem I, integrated with CMOS sensor circuits.
