消化管出血に対するNBCAを用いた塞栓術

抄録

Selective transcatheter arterial embolization (TAE) for gastrointestinal hemorrhage (GIH) has been proposed as a less hazardous alternative to surgery, especially in high-risk patients, and is now considered as the first-line intervention for massive GIH after failed endoscopic treatment. N-Butyl cyanoacrylate (NBCA) is a permanent liquid embolic material with a marked hemostatic effect and a low incidence of re-bleeding. NBCA has been increasingly used for controlling nonvariceal GIH. The morbidity of bowel ischemic events after TAE using NBCA (NBCA-TAE) has been pointed out, however, a causal relationship between NBCA and bowel ischemia has not been clearly established. This article reviewed the indication and role of NBCA-TAE while describing the behavior of NBCA within the circulation, administration techniques and therapeutic outcome, so as to outline the appropriate use of NBCA.