日本インターベンショナルラジオロジー学会雑誌
Online ISSN : 2185-6451
Print ISSN : 1340-4520
ISSN-L : 1340-4520
NBCAの臨床応用-NBCAの安全な使用に向けて-
NBCAの基礎,使用時の注意
上田 達夫杉原 史恵斉藤 英正白井 清香藤綱 隆太朗松本 大河林 宏光汲田 伸一郎
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2023 年 38 巻 1 号 p. 2-7

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NBCA (n-butyl-2-cyanoacrylate) is a cyanoacrylate-based liquid adhesive used for endovascular interventions and has a major role in managing vascular abnormalities, bleeding, and many vascular diseases. NBCA reacts with ionic solutions such as blood or normal saline, and starts polymerization immediately causing vascular embolization. NBCA is typically used in combination with lipiodol for intravascular embolization to provide radiopacity and achieve an appropriate polymerization time. The embolic effect is permanent and has a strong embolic effect that does not depend on coagulation parameters, but it requires proficiency in handling due to the risk of serious ischemic complications and adherence to the catheter if not used properly. This article introduces the basics of NBCA such as its characteristics, precautions / preparations for use, mixing ratio, tips for injection, indications, contraindications, and possible complications, for safe use of NBCA.

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