Abstract
We have bio-chemically realized Artificial Intelligence by using DNA reactions, which is composed of a well-known as oscillating DNA reactions, the seesaw gate reaction. Through biochemical experiments, we confirm that mismatched interact-able DNA sequences can adapt to perturbations of environmental change, which is caused by making point mutation in an input sequence. Based on this result, we model this reaction by using abstract chemistry and confirm that the model exhibits the same behavior as biochemical experiments. Through computational simulations show that this DNA reaction can compose the logic gate bio-chemically.