Abstract
Primary liposarcoma of the mediastinum is very rare. We present a patient with a primary mediastinal liposarcoma which was characterized by dedifferentiation. Most parts of the tumor showed dedifferentiation, so histologic examination revealed a solitary fibrous tumor at the first operation. Eighteen months after the initial resection, computed tomographic scanning showed the presence of a mass in the posterior mediastinum. We resected the mass, of which the final pathologic diagnosis was recurrent dedifferentiated liposarcoma.