Abstract
A 62-year-old male who had a history of asbestos exposure was referred to our center because of an abnormal mass shadow in the right upper field on plain chest radiograph. Computed tomography showed an 11-cm right chest wall tumor attached to the 2nd-4th ribs and results of a biopsy performed under CT yielded a sarcomatoid type of mesothelioma. Systematic examinations did not show any metastasis and the patient underwent six courses of Cisplatin and Pemetrexed chemotherapy. After chemotherapy, a partial response was achieved and he underwent right extrapleural pneumonectomy. Pathological examinations revealed localized malignant mesothelioma (pT2N0M0) and the surgical margin was negative. After the operation, radiotherapy was performed for the right chest wall and no relapse had been observed as of about six months. This is a very rare and important operative case of localized malignant mesothelioma markedly responsive to chemotherapy.
