Clinical study of seven surgical cases of thymic carcinoma

Abstract

Seven patients who received thymectomy at our hospital between 1998 and 2018 were clinically studied. The average patient age was 58.0 years old, including three males and four females. The average tumor diameter was 6.1 cm. The histological types were squamous cell carcinoma in five cases and undifferentiated carcinoma in two cases. The five-year survival rate was 57.1%. UICC8th p-Stage 1: two cases, 3A: one case, 4A: one case, and 4B: three cases, with only 4B: one case was Ef3. after conducting four courses of preoperative CBDCA+PTX. The operative method was a median sternotomy in all cases, with a left thoracotomy through the fourth rib additionally conducted in one case. Mediastinal lymph node resection was performed in six cases. Extended thymectomy and combined resection of the invaded organs were performed in each case, with postoperative radiation therapy conducted in all cases. Two patients underwent postoperative chemotherapy. We encountered two cases of relapse-free survival, one case of long-term survival following recurrence, and four cases of cancer death. In order to improve the treatment results of thymectomy, complete resection and multidisciplinary therapy are important. CBDCA+PTX is effective for chemotherapy. It is considered that Ef3. may be associated with long-term survival.