Abstract
A 63-year-old male patient was referred to our hospital due to two masses in the right lung on chest X-ray film, one of which was located in the middle lobe and the other in the lower lobe.
Transbronchial lung biopsy was negative for malignancy.
Microscopically, the specimens obtained by bilobectomy of the right middle and lower lobe showed proliferation of xanthoma cells and lymphocytes, and the histological diagnosis was multiple pulmonary xanthogranuloma originating separately in the middle and lower lobe.
Though xanthogranuloma is classified as an inflammatory pseudotumor, its pathogenesis remains to be fully elucidated.
As it is often difficult to differentiate is from lung cancer, exploratory thoracotomy and resection should be considered for definitive diagnosis.