2016 Volume 36 Issue 4 Pages 717-721
We conducted a retrospective analysis of the clinicopathological findings, operative procedures, complications and prognosis in patients with perforated colorectal cancer. From January 2000 to December 2013, we performed surgery for 21 cases of perforated colorectal cancer. The mean age was 76 years (50-100 years). Perforation was observed at the tumor site in 12 cases, and proximal to the tumor-affected site in tumor in 9 cases. The perforation was labeled as a free perforation in 12 cases. Histologically, the disease was diagnosed as stage Ⅱ in 7 cases, stage Ⅲ in 9 cases, and stage Ⅳ in 5 cases. Tumor resection was performed in 18 cases, including 15 who underwent lymph node dissection (D2 or D3), and 3 who underwent palliative colostomy. The mortality rate was 4.8%, and the morbidity rate was 47.6%. The 5-year disease-specific survival rate was 75%. Recurrence occurred in 4 cases, and manifested as liver metastases in 3 cases, lung metastases in 2 cases, peritoneal dissemination in 1 case, and bone metastasis in 1 case. Therefore, it is believed that radical surgery with lymph node dissection contributes to improved prognosis in patients with perforated colorectal cancer, provided the patients can tolerate the operation.