Abstract
The electrochemical methods have recently applied to the detection of ion and molecule recognitions based on supramolecular assembly, although many methods have been used to the detection. The electrochemical methods have many advantages, such as simple instrument and operation, and high sensitivity. Moreover, the electrochemical methods can apply to the detection even in the case of the absence of the electrochemical activity in both host and guest molecule, if the electroactive species, such as ferrocene, were introduced to the host or guest molecule, or the electrochemical impedance spectroscopy was used. The electrochemical methods were widely used in detection of bio-logical substance, such as DNA and enzyme, by means of modified electrode based on the self-assembly. In this paper, first, four electrochemical methods and modification methods of the electrode were briefly introduced, and then ion and molecular recognition by means of modified electrode was reviewed. Especially, we focused on and reviewed the reports mainly published in 2007 for the electrochemical detection of the biological substances, such as DNA and en-zyme, by means of modified electrode based on the self-assembly.
