2014 年 5 巻 2 号 p. 82-86
Rushton bodies, also known as hyaline bodies, are often observed in radicular cysts. The purpose of this study is to investigate the histopathological characteristics of Rushton bodies in radicular cysts and discuss the pathogenesis with a review of the literature. Histopathologically, Rushton bodies, which are localized in the cyst-lining epithelium, showed a linear, straight, curved or hairpin-like appearance, sometimes with calcification. The bodies were also associated with degenerated or apoptosis-like, cyst-lining epithelial cells, fibrin, erythrocytes, hemosiderin, and/or cholesterol crystals. In addition, lipid-like granules, CD68-positive foamy macrophages or siderophages were observed near Rushton bodies. These findings suggest that the pathogenesis of Rushton bodies is associated with both theories of hematogeneous and epithelial cell origin. The present study also supports the notion that these theories are also related to cholesterol crystals with accumulation of lipids and macrophages. Furthermore, based on the present study, oral surgeon and dental clinicians should completely remove the cyst-lining epithelium associated with Rushton bodies of microstructures in radicular cyst components.
