2003 Volume 23 Issue 5 Pages 373-381
In this article, we describe the “genome-based medicine” as a new horizon of medicine driven by genome information and discuss crossover points genome-based medicine and medical informatics. And moreover, we focused on the disease model that is expected to be a new frontier in medical informatics. The disease model and simulation supports the “systems medicine” as system-level understanding of disease that is based on the comprehensive genomic data.