Features and study on the use of DiaPack3000 and MAST III

Abstract

Recently, the number of patients with type I allergic disease has been increasing. The specific IgE test is one of the important tests for the diagnosis and treatment of allergic diseases. In our laboratory, we utilize two analyzers for specific IgE, namely, DiaPack3000 and MAST III. We can properly use these analyzers depending on the situation. We evaluated these analyzers and compared their performances. For specimens from pediatric departments, it is difficult to obtain specimen enough, and reducing amount of specimen is an important issue. Therefore, we also compared the standard volume method and the reducing volume method. Concerning the class correlation between MAST III and DiaPack3000, good correlation was found for Japanese cedar, Dermatophagoides farinae, and cat dander. On the other hand, for egg whites and ovomucoid, a weak positive and partial divergence was observed. However, the possibility of clinically affecting the results is unlikely. Therefore, it seems that it can cope with the transition from screening by MAST III to follow-up observation by DiaPack3000. For DiaPack3000, a good correlation was found between the standard volume method and the reducing volume method. We believe that further clinical support can be expected by increasing the number of items examined reducing volume by reducing the sample volume.