Basic study of the reagent ‘Elia calprotectin 2’ for fecal calprotectin measurement: Fecal calprotectin measurement

Abstract

We performed basic evaluation studies of the reagent ‘Elia calprotectin’ based on the principle of sandwich fluorescence enzyme-linked immunoassay for the measurement of fecal calprotectin. Results showed that the CVs of within-run precision and between-day precision were less than 7.0% and dilution linearity was also good. In addition, the correlation with ‘Calprotectin Mochida’ used for comparison was good (y = 1.071x + 38.3, r = 0.789, n = 66). Positive and negative concordance rates were also good (87.2%). ‘Elia calprotectin’ showed sufficiently good basic performance for routine use.