Utility of rapid on-site cytologic evaluation with endoscopic ultrasound-guided fine needle aspiration for pancreatic solid tumors and the role of cytotechnologists in this diagnostic method

Abstract

The efficacy and usefulness of rapid on-site cytologic evaluation (ROSE) with endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) biopsy in our hospital over the past 9 years in 35 patients with pancreatic solid tumors were reported. The centesis of the biopsy specimens was 2.2 times on average and the sampling rate was 100%. The most important diagnostic report was malignancy confirmation; the diagnostic accuracy was 97.1%, sensitivity was 96.3%, and specificity was 100%. The sampling rate, specificity, sensitivity, positive predictive value, and diagnostic accuracy were high. Since the introduction of EUS-FNA, ROSE has contributed to enhancing the collaboration of staff members between the pathological and gastroenterological departments. EUS-FNA with ROSE in this field is now considered to be a useful method of obtaining samples reliably and completing the test with minimal puncture.