2019 Volume 68 Issue 4 Pages 794-799
The patient was an 82-year-old woman who had been diagnosed as having IgG-κ multiple myeloma by her previous doctor in April 2015. She was referred to our hospital because she was suspected of having intraductal papillary mucinous neoplasm when she visited her previous doctor owing to stomachache in October 2017. The patient’s serum formed cryoglobulins at room temperature (22℃) as well as at 4℃. Needlelike crystals were also observed under a light microscope for serum samples stored at 4℃, and they were observable with the naked eye for samples stored at room-temperature. Cryoglobulins were resolved at 37℃, and the crystals were resolved at 42℃. The crystals were of the monoclonal IgG-κ type, as determined by various examinations. The patient does not have apparent symptoms at present; however, it is suggested that we need to pay attention to various symptoms triggered by future cold exposure.
