2020 Volume 69 Issue 3 Pages 340-345
A soluble IL-2 receptor (sIL-2R), the circulating form of the IL-2 receptor, localizes on lymphoid and some cancer cells and is used widely as a biomarker for adult T-cell leukemia and non-Hodgkin lymphoma. In this study, we evaluated the performance of a chemical luminescence test reagent LUMIPULSE Presto IL-2R for the measurement of serum soluble IL-2 receptor using an automated immune chemiluminescent system LUMIPULSE L2400. The coefficients of variation for within-run and between-day reproducibilities ranged from 0.7% to 3.3%. Linearity was observed up to about 80,000 U/mL and the lower limit of detection was 2.79 U/mL. A good correlation was observed between Immulyze IL-2R and LUMIPULSE Presto IL-2R. In conclusion, the analytical performance of LUMIPULSE Presto IL-2R seemed acceptable for routine clinical laboratory tests.
