2021 Volume 70 Issue 2 Pages 243-251
We compared the performance of two glucose analyzers on the basis of the glucose oxidase immobilized enzyme membrane electrode method for both plasma and whole blood measurements. Regarding their accuracy, both analyzers showed good accuracy, and within-run and between-day reproducibilities were also confirmed to have good precision. A high correlation was confirmed for plasma and whole blood samples analyzed with the current equipment and other measurement methods. In whole blood measurement, samples with a high hematocrit showed greater fluctuations of glucose levels, and it was confirmed that the hematocrit greatly affected the whole blood measurement. However, changing the routine work to whole blood measurement eliminates the need for centrifugation, which can lead to more efficient measurement operations and a shorter TAT. As a result, it is conceivable that efficiency could lead to clinical contribution. There are various samples used for blood glucose examination, such as arterial blood, venous blood, plasma, serum, whole blood, and there are multiple methods, and we considered that the measurement accuracy could be ensured by understanding and using the characteristics of samples and methods.
