2022 Volume 71 Issue 1 Pages 143-147
A total of 136 cases were reported as carbapenem-resistant Enterobacteriaceae bacterial infections (CRE infections) in Niigata Prefecture (excluding Niigata City) between September 2014 and December 2020. For these cases, we investigated 127 strains provided by medical institutions for drug resistance gene possession. Of the 127 strains we investigated, the carbapenemase gene was detected in five strains (3.9%). The genotype of four strains was IMP-1 and that of the remaining strain was IMI-1. Strains with the IMP-1 genotype have been reported from many areas nationwide, whereas those with the IMI-1 genotype are rare, which were detected in three cases nationwide as of 2019. The IMI-1-genotype strain carrying the carbapenemase gene was detected in the Enterobacter cloacae complex isolated from the exudate of a male patient in his 70s. CRE infections are defined in the Infectious Diseases Control Law and are important for infectious disease control. The detection rate and type of carbapenemase gene differ depending on the region, so it is important to determine the situation and characteristics of a certain region.
