2023 Volume 72 Issue 3 Pages 465-470
We experienced treating a case of invasive Haemophilus influenzae infection with H. influenzae serotype e (Hie). The patient was a woman in her 80s. Owing to hemodialysis due to end-stage renal disease, she was an outpatient at the nephrology department of our hospital. She was admitted to our hospital with a fever during hemodialysis, and a bacterial infection was suspected. H. influenzae was isolated from two sets of blood cultures (three cultures each) and sputum culture collected the same day, and invasive H. influenzae infection caused by bacterial pneumonia was diagnosed. A capsular type test of the detected bacterium was performed, and both strains derived from blood cultures and the strain derived from sputum culture were determined to be serotype e. Reports of invasive H. influenzae infection with H. influenzae serotype b (Hib) have declined since the introduction of routine H. influenzae type b (Hib) vaccine. Conversely, reports of invasive Haemophilus influenzae infections due to nontypeable Haemophilus influenzae (NTHi), which were originally thought to be frequent local infections such as otitis media and bronchitis, have increased. On the other hand, there are few reports on other capsular types, and future trends are important.
