2024 Volume 73 Issue 1 Pages 180-187
A 50-year-old woman presented with a dimple in C area of the right breast since 1 year ago, also redness and pain in AC area of the left breast since three months ago. Breast ultrasonography detected the hypoechoic mass measuring 18 × 15 × 14 mm and 41 × 39 × 31 mm, respectively. Histopathological examination by US-guided core needle biopsy diagnosed invasive ductal carcinoma (IDC) (luminal A) and IDC (triple negative), respectively. Contrast-enhanced computed tomography (CT) revealed metastasis of the lung. Chemotherapy was started based on the diagnosis of bilateral breast cancer with metastasis of lung. Seventeen months after the diagnosis of breast cancer, the patient was taken to the hospital due to unconsciousness. Then craniotomy lumpectomy was performed for metastasis of the brain. Two years later, contrast-enhanced CT detected an enlarged low density nodule in the right lobe of the thyroid gland. Thyroid ultrasonography detected the internal hypoechoic mixed nodule in the right lobe of the thyroid gland, that was 19 × 19 × 23 mm in size and irregularly shaped. Compared with the thyroid ultrasonographic image of 12 years ago, the present ultrasonography showed the nodule in the right lobe, protruding slightly outward. Histopathological examination by US-guided fine needle aspiration cytology revealed metastasis of breast cancer. Breast cancer can metastasize to multiple organs in the terminal stage, but metastasis to the thyroid gland is relatively rare and has been reported in a few cases. We have reported this case with a review of the literature.
