Calcium or paraffin deposition causes the decrease of tubig diameter. It is one of the problems in many oil fields that the increase of pressure drop is resulted from the decrease of tubing diameter. The effects of presence of smaller diameter section in a tubing string in two phase vertical flow were studied. The measurements were carried out at atmospheric pressure using air as gas and water as liquid. The vertical flow strings used in the experimental works were consisted of the about 5-m-long and 2.5-cm in diameter main section and the smaller dia meter section placed in the middle part of main section (shown in Fig. 1). The smaller size pipes were long between 2-cm and 50-cm and 0.52cm in diameter. From the results of the tests, the correlation was developed. The pressure drop in smaller size section is able to be calculated by using Eq. (5) and Eq. (6) with Fig. 7. The pressure drop is expressed in terms of the pipe length, liquid flow rate and gas liquid ratio.