Abstract
This study explored the experiences of pre-exposure prophylaxis (PrEP) users and its meaning for their relationships
with people living with HIV. Over an 18-month period, we conducted semi-structured interviews with three male
PrEP users who had sex with men. We performed a qualitative analysis of the relationship between PrEP users and
HIV-positive individuals. PrEP enhanced users’ confidence in their ability to avoid infection, reduced fear of HIV,
and achieved a sense of control over infection. Furthermore, compared with using condoms which required consent
from sexual partners, PrEP enabled users to take the lead in preventive actions, shifting the responsibility for
prevention away from others. Additionally, PrEP facilitated communication with HIV-positive individuals, allowing
them to be perceived not solely as HIV-positive individuals, but rather as individuals. From this perspective, PrEP
use provided an opportunity for rebuilding relationships between PrEP users and HIV-positive individuals and
established new interpersonal dynamics.