Journal of Oral Tissue Engineering
Online ISSN : 1880-0823
Print ISSN : 1348-9623
ISSN-L : 1348-9623
ORIGINAL ARTICLES
Osteoinductive Activity of 3D-modeling Titanium Scaffold with BMP
Hironari FUYAMADAShin MIYAMAETatsuhide HAYASHITatsushi KAWAIMasami HATTORI
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ジャーナル フリー

2016 年 13 巻 3 号 p. 110-116

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Various methods are used to construct the scaffolds used for bone regeneration. We built a three-dimensional (3D) porous scaffold from layers of pure titanium powder melted with a powerful electron beam. We then added bone morphogenic protein to this scaffold and examined its ability to induce new bone. The surface of the scaffold was rough and the pore size was approximately 1000 μm. Three weeks after implantation, little new bone was observed inside the scaffold, whereas much bone formation had been induced around the scaffold. This study showed that a complex 3D porous scaffold can be fabricated using the electron beam melting method, suggesting that this method is effective for the construction of optimal shapes for new bone induction.

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© 2016 by Japanese Association of Regenerative Dentistry
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