Biological Safety of Mixed Acid Heat Treatment in SLM (Selective                    Laser Melting Technique) Titanium Mesh

Shihoko INUI; Kayoko YAMAMOTO; Nahoko KATO-KOGOE; Yoichiro NAKAJIMA; Kazuya INOUE; Hiroyuki NAKANO; Seiji YAMAGUCHI; Azumi HIRATA; Yoichi KONDO; Takaaki UENO

doi:10.11223/jarde.16.27

ORIGINAL ARTICLES

Biological Safety of Mixed Acid Heat Treatment in SLM (Selective Laser Melting Technique) Titanium Mesh

Shihoko INUI , Kayoko YAMAMOTO, Nahoko KATO-KOGOE, Yoichiro NAKAJIMA, Kazuya INOUE, Hiroyuki NAKANO, Seiji YAMAGUCHI, Azumi HIRATA, Yoichi KONDO, Takaaki UENO

Author information

Shihoko INUI Corresponding author
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
Kayoko YAMAMOTO
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
Nahoko KATO-KOGOE
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
Yoichiro NAKAJIMA
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
Kazuya INOUE
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
Hiroyuki NAKANO
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
Seiji YAMAGUCHI
Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Japan
Azumi HIRATA
Department of Anatomy and Cell Biology, Osaka Medical College, Osaka, Japan
Yoichi KONDO
Department of Anatomy and Cell Biology, Osaka Medical College, Osaka, Japan
Takaaki UENO
Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan

Keywords: Selective Laser Melting technique, titanium mesh, mixed acid heat treatment

JOURNAL FREE ACCESS

2018 Volume 16 Issue 1 Pages 27-31

DOI https://doi.org/10.11223/jarde.16.27

Details

Abstract

A titanium (Ti) mesh using the Selective Laser Melting (SLM) technique was subjected to surface modification by mixed acid heating, and it was applied to a rat calvarial bone defect model. Safety of the mixed acid heat treatment on the surface was evaluated by investigating the inflammatory response based on macroscopic and microscopic findings. Worsening of inflammatory reactions was not observed in the SLM Ti mesh-embedded group at 2, 4 or 7 weeks. These results suggest that mixed acid and heat treatment surface modification Ti mesh is safe.

Corresponding author

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