Abstract
The aim of this study was to examine the effect of alumina blasted titanium disks, prepared by blasting with 7 different graded sizes of alumina particles, on osteoblast-like MG-63 cells. Following an evaluation of the surface conformation and the average surface roughness, the cell morphology, initial cell adhesion, cell proliferation, alkaline phosphatase (ALP) activity and osteocalcin (OC) production were examined. Both the cellular differentiation (ALP activity, OC) and initial cell adhesion increased with a coarser surface. However, differences in surface roughness had no significant effect on cell proliferation.
