Bone Response after Tooth Extraction in Ovariectomized Rats

Abstract

Few studies have investigated the bone healing of the extracted socket in osteoporosis. The aim of this study is to evaluate the bone response of mandibular incisor extraction in ovariectomized rats using titanium alloy screw.
Ovariectomy (OVX) or sham operation was performed at 9 weeks of age. We measured animal body weights each three week to observe the development situation. The titanium alloy screws were placed into the cavities of the mandibular incisor extraction. At 3, 6 and 9 weeks post-insertion, histological observation were performed.
Findings in the healing process of the extraction socket after insertion of a titanium screw differed between the Control and OVX groups.
The study results indicate that osteoporosis has affect on socket healing after the extraction of ovariectomized rat mandibular incisors. Therefore we may need to consider osteoporosis in patients of bone response after tooth extraction.