Changes of the Constituents in Serum and Aortic Tissue by the Differences of the Kinds of Feed -SHR-

抄録

Constituents in serum and aortic tissue by the differences of kinds of feed were measured using 90SHRs after 2-3 months from birth.
Three kinds of feed were given SHRs, namely first of standard feed (oriental solid) and water, second of standard feed and 10% sucrose solution as drinking water, and third of standard feed whose 40% of total calorie was replaced with lard and water.
1) The constituents as well as lipids and binding hexose were changed in serum and aortic vessel wall by the administration of sucrose or lard.
2) The modes of changes of constituents differed among oriental standard feed group, sugar group and lard group. And the changes differed between 3-8 week feeding and 10-12 month feeding, too.
3) Changes of lipids and of binding hexose were not the same in serum or aortic tissue. Namely, both substances must be considered independently as risk factor of vessel injury.
4) Time discrepansy of changes of lipid binding-hexose was found between concentration in serum and amount in aortic tissue.