抄録
The effect of vitamin E on the lipid metabolism of erythrocyte membrane of experimental hypercholesterolemic rabbits was examined. Rabbits were divided into two groups. Group C: rabbits fed by a hypercholesterol diet. Group E rabbits fed by a hypercholesterol diet containing vitamin E. Erythrocyte Membrane lipids and lipids in the thoracic aorta were analysed.
Free cholesterol in the erythrocyte membrane of group C was not so much increased as that of group E. In group E, the decrease of polyunsuturated fatty acids (PUFA), particulary C18=2, C18=2 of erythrocyte membrane phospholipid was inhibited. Phospholipids in the aorta of group E contained more PUFA than that of group C. These data suggested that vitamin E had an important effect on membrane lipid metabolism.
