Abstract
Proline-rich protein (PRP) is present in chylomicron and d>1.21 fraction of human plasma. PRP was separated from lipoprotein-depleted serum by absorption to Intralipid. Antiserum to PRP was raised by rabbit and the serum concentration was assayed by single immunodiffusion. PRP was correlated to serum total cholesterol and triglyceride, VLDL-cholesterol and VLDL-trigly-ceride and Apo B, C-II, C-III. These data suggested that PRP relates to the metabolism of TG-rich lipoproteins.