Lipids metabolism during prolonged fasting (10-days complete fasting) has been studied in 23 psychosomatic patients (9 male and 14 female, average 29.2 y. o.), who had no metabolic disease.
During the fasting period, serum F.F.A. and Cholesterol levels significantly elevated (p<0.001).
In the lipoprotein fraction, LDL-cholesterol and LDL-triglyceride (d: 1.006-1.063) significantly elevated by fasting (p<0.001), but VLDL-triglyceri de (d;<1.006) decreased (p<0.05).
The increase of LDL reflected the increase of LDL2-fraction (d; 1.019-1.063), and this was related to thyroid hormone levels. T3 levels decreased during prolonged fasting (p<0.01).
It was considered that increase of LDL was related to the decrease of LDL-receptor activity which was dependent on T3-levels.
