抄録
The levels of serum apolipoproteins, lipoproteins and lipids in 36 patients undertaking coronary angiography were measured and their relations with the severity of coronary stenosis were evaluated.
Also, correlation between variables of stenosis (+) group and those of stenosis (-) group were evaluated.
There was a significant positive correlation between the severity of coronary stenosis and the serum level of apolipoprotein B (p<0.05).
The serum apolipoprotein B was significantly higher in the stenosis (+) group (p<0.05).
Apolipoprotein B/apolipoprotein A-II ratio in serum was also significantly higher in the stenosis (+) group (p<0.01).
The serum HDL3 showed significantly lower level in the stenosis (+) group. From these findings apolipoprotein B may be an atherogenic factor and HDL3 may be a antiatherogenic factor. Moreover, there were significant positive correlations both between the serum HDL2 and apolipoprotein A-I and between the serum HDL3 and apolipoprotein A-II, suggesting that they would have some relations one another.
