The effect of the β-adrenergic stimulant (β1 selective:denopamine, β2 selective:terbutaline) on the serum lipid levels of a rat were examined. The drugs were administered at a dose of 10mg/kg over a 4 week period. The terbutaline group showed higher total cholesterol levels with both a, normal diet and a 1% cholesterol diet that did those of the denopamine group. The terbutaline group showed higher VLDL and LDL cholesterol levels with a normal diet than did those of the denopamine group. Free fatty acid and free glycerol levels were significantly lower in denopamine group with a cholesterol diet than it was in those of the control group.
