抄録
A sedentary lifestyle adversely affects the successful prevention of coronary heart disease (CHD). Due to the methodological difficulties of it's quantitatively measuring daily physical activity, little is known about it's effect on serum lipid levels in the elderly. In this study we used the Life Corder (Kenz, Nagoya Japan), which is a pedometer that memorizes the patient's daily physical activity for up to 42 days semi quantitatively. We analyzed 33 elderly (over 65 year-old) men with CHD who visited our outpatient clinic. We measured the daily physical activity (mean step count/day (S), calculated mean energy of physical activity/day and calculated mean total energy expenditure/day (TE)), and exercise tolerance (VO2max/kg, ATVO2/kg) using treadmill exercise stress test. Serum lipid profiles were analyzed enzymatically after at least 12 hours fasting. The levels of serum total cholesterol were inversely correlated with TE: r=-0.45, P=0.0095. The levels of serum HDL cholesterol were significantly correlated with S: r=0.46, p=0.0084. Triglyceride did not correlate with the parameter of daily physical activity. Exercise tolerance did not correlate with serum lipid profiles. In elderly patients, daily physical activity was related to the serum lipid profile, which suggests that the improvement in daily physical activity could support secondary prevention by improving the lipid profiles in elderly patients with CHD.