Abstract
A pathological study on the cerebrovascular lesions was performed on 59 diabetic human autopsy cases and 292 non-diabetic cases (controls).
At first, the cerebrovascular lesions were observed macroscopically on all cases, and the correlation to ages was investigated.
Secondary, microscopical softening or subsoftening changes were observed on specimens obtained from bilateral ganglionic regions of 27 diabetic cases. Each findings was divided into five grades, and it's correlation to blood pressure, diabetic glomerular lesions, etc. were investigated.
Following results were obtained.
1. The cerebral softening was more frequent in diabetic cases than in controls, but the cerebral hemorrhage was more frequent in controls than in diabetic cases, as far as in macroscopical observation.
2. Microscopically, many softening and subsoftening changes were found in the basal ganglionic sections of the many diabetic cases that have revealed no obvious macroscopical changes. The severe changes were seen more frequent in hypertensive cases than in normotensive cases.
