抄録
Coronary arteries were obtained from 198 cases of accidental sudden death. The intimal surface was observed and the sclerotic lesions were separated according to the WHO classification into I: normal, II: slightly changed (lipid deposition, smoothly surfaced fibrous plaques), and III: moderately and severely changed (plaques with ulceration, necrosis and calcification). The extent of coronary atherosclerosis was estimated by the weight ratio of the sclerotic lesion (sclerotic weight ratio, S. W. R.: wet weight of lesions II and III/total wet weight). The relationship of sclerotic weight ratio (Y) to the following variables was analysed by using “Stepwise Regression forward selection procedure).” Variables: age (X1), thickness of subcutaneous adipose tissue at the navel (X2), body mass index (X3), liver weight (X4), right or left kidney weight (X5, X6), heart weight (X7), thickness of right or left ventricular wall (X8, X9), heart cavity volume (X10), and circumference of aorta or pulmonary artery (X11, X12). The relationship was expressed by the equation Y=0.679X1-0.168X2+0.743X3+0.004 X4-0.023X5+0.032X6+0.037X7+0.723X8-0.732X9-0.100X11-0.272X12-27.320. Out of 198 cases, 66 cases were diagnosed pathologically as myocardial infarction. The mean S. W. R. of infarction group was 25.8±3.6 (Mean±S. E.) whereas that of non-infarction group was 15.0±1.8. 2×2 table (infarction/no-infarction vs. S. W. R.<15.0/15.0<S. W. R.) shows that the occurrence of myocardial infarction was independent of the extent of coronary atherosclerosis.
