Breast Cancer
Online ISSN : 1880-4233
Print ISSN : 1340-6868
ISSN-L : 1340-6868
Case Reports
A Case of Mucinous Carcinoma of the Breast that Demonstrated a Good Pathological Response to Neoadjuvant Chemotherapy Despite a Poor Clinical Response
Junpei YamaguchiSadako Akashi-TanakaTakashi FukutomiTakayuki KinositaEriko IwamotoMiyuki Takasugi
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2006 年 13 巻 1 号 p. 100-103

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A 30-year-old woman presented with a right breast tumor. Mucinous carcinoma was diagnosed by core needle biopsy (T2: 5 cm N1 M0). Despite receiving a neoadjuvant anthracycline and taxane regimen, the patient demonstrated no clinical response (NC). Based on the patient's strong preference, we performed breast-conserving surgery. On histological examination, we observed widespread mucus and a few viable malignant cells, a Grade 2 therapeutic response. Neither optimal management procedures nor guidelines for chemotherapy for primary mucinous carcinoma of the breast have been established. It is a reasonable assumption, however, that discordance between the clinical response and therapeutic response to neoadjuvant chemotherapy may occur in cases of mucinous carcinoma.
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© 2006 by The Japanese Breast Cancer Society
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